2018 BioSys Projects


National PhD Projects


  • DIS3L2 in NMD – The involvement of DIS3L2 in nonsense-mediated mRNA decay and its functional networks in colorectal cancer, Supervisor: Luísa Romão, BioISI/INSA, Co-supervisor: Paulo Matos, BioISI/FCUL.
  • Map.miRNA34 – An integrative approach to tissue-specific effects of microRNA regulatory networks, Supervisor: Margarida Gama-Carvalho, BioISI/FCUL, Co-supervisor: Nham Tran, UTS (Australia).


  • IDSS-P4 – Intelligent Decision Support Systems for personalized prevention and clinical management of infectious diseases, Supervisor: Ricardo Dias, BioISI/FCUL, Co-supervisor: Francisco Couto, DI/FCUL


  • Mol4Health – Molecules for Health: cholesterol absorption and transporter proteins expression under the effect of bioactive molecules, Supervisor: Maria Luísa Serralheiro, BioISI/FCUL, Co-supervisor: Mafalda Bourbon, BioISI/INSA


  • Orphan CFTR mutations – Orphan CFTR mutations – from disease mechanisms to novel therapeutic opportunities, Supervisor: Carlos Farinha, BioISI/FCUL, Co-supervisor: Margarida Amaral, BioISI/FCUL and André Falcão, DI/FCUL



International PhD projects


  • GrapeResist2DownyMildew – Grapevine resistance to downy mildew: the innovative role of subtilisin-like proteases, Supervisor: Andreia Figueiredo, BioISI/FCUL, Co-supervisor: Gunther Buchholz, Institute for Plant Research (Germany)


  • Comput’Omics – Metabolomics and genomics of microbial infections and gut microbiome dynamics in patients undergoing allogeneic hematopoietic stem cell transplantation, Supervisor: Francisco Pinto, BioISI/FCUL, Co-supervisor: João Xavier, Memorial Sloan Kettering Cancer Center (USA)


  • GrapeVine17 – Remodelling of grape cell wall upon infection with biotrophic and necrotrophic pathogens, Supervisor: Ana Margarida Fortes, BioISI/FCUL, Co-supervisor: John Moore, Stellenbosch University (South Africa)


  • Resist2antimalarials – Resistance to antimalarials – a pharmacogenomics approach for both parasite and human host, Supervisor: Jose Pedro Gil, BioISI/FCUL/Karolinska Institute, Co-supervisor: Volker M. Lauschke, Karolinska Institute (Sweden).


  • S100B@Alzh – The role of secondary modification of S100B in protein aggregation and its influence on Alzheimer’s disease pathology, Supervisor: Cláudio Gomes, BioISI/FCUL, Co-supervisor: Andreas Grabrucker, Univ Limerick (Ireland)


  • SLC26.A9 – Cystic Fibrosis Therapies through Non-CFTR Anion Channels/ Transporters, Supervisor: Margarida Amaral, BioISI/FCUL, Co-supervisor: Karl Kunzelmann, URegensburg (Germany).